Messi vs. Mexico’s Best: Will MLS Dominate the Leagues Cup Again? **

The Leagues Cup enters its knockout stage with Lionel Messi’s Inter Miami and three other MLS teams battling Liga MX’s top contenders—including Tigres and Toluca—for the title. Can MLS secure another victory, or will Mexico finally break through?

By Chris Posiano

August 19, 2025 at 4:27 AM

7,749 views

After a competitive group stage, the Leagues Cup has narrowed down to eight teams—four from MLS and four from Liga MX—setting up a thrilling knockout round. The quarterfinals kick off on August 20 with a quadruple-header, as top clubs from both leagues clash for the championship.

MLS is represented by reigning MLS Cup champions LA Galaxy, Seattle Sounders, Orlando City, and the star-studded Inter Miami, featuring Lionel Messi. Meanwhile, Liga MX brings powerhouse Tigres, 2024 CONCACAF Champions Cup winners Pachuca, Clausura champions Toluca, and Puebla. The Columbus Crew, the previous year’s champions, exited early, meaning a new winner will be crowned.

While MLS teams have dominated the tournament in its first two editions, Liga MX clubs are eager to claim the title for Mexico. Tigres and Toluca, in particular, are strong contenders, carrying the hopes of their league into the knockout stage. But with Messi leading Inter Miami, MLS fans are optimistic about another victory.

Only four teams will advance this week, and the stage is set for intense battles. Will MLS continue its reign, or will Liga MX finally break through? The road to the Leagues Cup final begins now.

Watch the Leagues Cup knockout round live on MLS Season Pass.